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How Alcohol Affects Your Body And Your Brain

When you ingest alcohol, it quickly enters your digestive tract and is absorbed into your blood. That blood makes its way to your liver, where it metabolizes alcohol at a constant rate. Regardless of how much alcohol you consume.

On average a single 1.5oz shot of 35% alcohol or a 12oz 4% beer can be fully metabolized in one hour. When you consume alcohol faster than your liver can metabolize it, alcohol builds up in your bloodstream. Your blood alcohol content (BAC) rises, and alcohol has pervasive effects on your brain. You feel drunk.

Drinking + TGAC and the Liver

Alcohol metabolism induces the production of free‐radicals that cause damage to your liver through oxidative stress and the creation of Acetaldehyde, an extremely toxic by product formed when alcohol is metabolized in the liver. Acetaldehyde toxicity is one of the main causes of hangovers.

Asghar and Masogo (2008) in a landmark paper clearly demonstrated that silymarin (the active ingredient in St Marys Thistle, and the first ingredient in TGAC) was a powerful agent that protected biological systems against oxidative stress such as that induced by alcohol consumption.

Because Alcohol is metabolized at a constant rate in your liver by the enzyme ADH, any alcohol that can’t be processed by ADH backs up, circulates through your bloodstream and makes you drunk.

Dihydromyricetin, (the active ingredient in Oriental Raison Tree and the second Ingredient in TGAC) enhances the ADH enzyme, speeding up the liver’s ability to metabolize alcohol, and flushing it out of your system. It also has the same effect on the enzyme that metabolizes acetaldehyde (ALDH).

The faster your liver can metabolize alcohol and acetaldehyde, the faster it can resume its normal duties. This results in decreased damage done by alcohol to the liver.

Drinking + TGAC and the Brain

When you consume alcohol faster than your liver can metabolize it, alcohol builds up in your bloodstream. Your blood alcohol content (BAC) rises, and alcohol has pervasive effects on your brain and you begin to feel drunk.

 When alcohol reaches your brain it affects two different neurotransmitters. Simply put, neurotransmitters are chemicals your brain cells use to control emotions, movement, behaviour, and thought processes. Two categories of neurotransmitters are inhibitory and exhibitory. Inhibitory neurotransmitters have a calming effect and “slow” things down. Exhibitory neurotransmitters increase energy levels and brain activity.

One neurotransmitter affected by alcohol is GABA. Alcohol binds to GABA receptors in your brain and amplifies its effect. As the brain receives a stronger message from GABA, you begin to feel calm, and your heart rate slows down.

When you continue to drink, GABA signals are amplified further and further. Eventually, you experience loss of motor control, inhibitions are lowered, and your speech begins to slur.

(Additionally it is worth noting that when alcohol is consumed at a dangerous level, your breathing and heart rate can slow down to the point you can experience coma, or even death.)

TGAC works because Dihydromyricetin blocks the Alcohol from affecting GABA Receptors. Dihydromyricetin binds to GABA receptors in the brain and blocks the effect alcohol has on GABA receptors. [1] Theoretically, this should reduce certain feelings related to intoxication as alcohol is only amplifying the exhibitory neurotransmitter Glutamate (another neurotransmitter affected by alcohol). This theory was put to the test, and has held up in various studies.

 When TGAC is taken before drinking, alcohol can’t amplify GABA and you don’t feel as intoxicated. When TGAC is taken after drinking, it can accelerate the rate at which one sobers up. TGAC’s benefit on the brain isn’t just limited to GABA receptors. Dihydromyricetin is also a potent antioxidant able to prevent damage done by alcohol to dendrites.

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The Great Benefits Possible…

Get Drunk Slower

GET DRUNK SLOWER

sober up faster

SOBER UP FASTER

protect your liver from drinking

PROTECT YOUR LIVER

headache from drinking too much

ELIMINATE HEADACHES

PREVENT BRAIN DAMAGE

END PICKLED SLEEP

SLEEP THROUGH THE NIGHT

End Embarresment

END EMBARESSMENT

DRINK GRACEFULLY

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The Good Word on the Cure!